One day, we received a very special call. One that brought us back to the lab bench, surrounded by pipets, nitrile gloves, buffer bottles, and the everlasting dream of seeing our results published in a high impact journal. We got the opportunity of publishing in Cell! Well, more precisely, on its cover.
Dr Salvador Aznar Benitah, from IRB Barcelona, contacted us with the great news: he was about to publish, not only one, but two papers! Both in the same volume of this top journal. His team had just made some breakthroughs into the regulation of circadian rhythms and he wanted us to design a cover that would illustrate these discoveries.
We learnt long time ago how our bodies are regulated by our internal clock, but actually, they had discovered that there isn’t only one, but plenty biological clocks ticking within us! With their two publications analysing circadian regulation on the skin and the liver, they showed how our tissues regulate their clocks in response to daylight and darkness, independently from the brain. Also, they realised that there is a crosstalk between the different clocks, which is necessary to ensure synchronization and proper function of our body. Without a doubt, this is a key discovery, since alterations of these rhythms have been associated with premature ageing and even predisposition to the generation of tumours.